Charlie Stross
Needle-Free: New Nano-Vaccine Effective Against All COVID-19 Variants
(Administered as intranasal spray, stable at room temperature, broad spectrum. No word on whether/when it'll be available.)
https://scitechdaily.com/needle-free-new-nano-vaccine-effective-against-all-covid-19-variants/
Charlie Stross
@goatsarah Same (except I last caught it in August, not last week).
Charlie Stross
@cobweb Load it into cropduster tanks and spray it over cities inhabited by anti-vaxxers and chemtrail conspiracy theorists!
Cobweb, Currently Clean on OPSEC; Grungler; Ⓐ ⁂ Ⓐ ⁂
@cstross can’t wait to shoot this straight up my nose.
Feòrag
@cstross @cobweb Claiming that this is being done might actually get the fuckers to mask up!
Graydon
@cstross @cobweb As described, that'd work!
You could probably mist it into shared airspaces via something indistinguishable from a humidifier rather more economically.
Charlie Stross
@graydon @cobweb As @feorag notes, we should *tell* the conspiracy theorists it's in the chemtrails! That way they'll suddenly see sense (FSVO "sense") and start masking up.
Charlie Stross
@SimonCHulse It's showing promise in testing ... on mice. Needs three phases of human clinical trials before it's demonstrated to be safe *and* efficacious. A lot of meds never make it past that hurdle: we've had credible anti-AIDS vaccines for decades—but only in mice (they failed in humans).
Ko Simon toku ingoa :tinoflag:
@cstross they better get it out as fast, and as cheap, as possible instead of just being another vapourware drug
Quinn Norton
@cstross im a little late to this one, but i really hope it works. nasal vaccines have been really troublesome for adverse events and have often died in phase 1 or 2, but it would be so great if we could get one of these working -- putting the immunity *where* the infection happens in a big fucking deal for stopping it, not just reacting to the infection. fingers crossed!
Charlie Stross
@quinn Meanwhile, over in the Excited Snakes of Amurrica, RFK Jr's best buddy is trying to get FDA approval for the fricken' *polio vaccine* withdrawn.
I swear I despair of humanity.
Quinn Norton
@cstross I know the evil is powerful, charlie, but i believe the FDA's endless bureaucracy and glacial pace will defeat all its enemies, including itself.
Quinn Norton
@cstross As for new drugs, and indications... well i'm glad a moved to the EU 😬
Charlie Stross
@quinn Yes but, fricken' RFK Jr! In charge of public health! In a country that's got an agricultural sector that seems to be TRYING to generate a human-viable H5N1 flu strain! (Incoherent screaming)
Quinn Norton
@cstross we gotta take this timeline one day at a time, man. ❤️ 😂
Shouty person
@cstross
One thing that’s not mentioned in the article is whether it’s a live vaccine or not. Most intra-nasal vaccines so far are live. Live vaccines are very effective, but you can’t give them to immunocompromised people.
Charlie Stross
@clacksee It's definitely not a live vaccine. Details in the article—it's peptide sequences from the virus coat protein embedded in a synthetic nanoparticle.
Shouty person
@cstross
Oh, that’s even better!
Charlie Stross
@clacksee It is, however, only a runaway success in mice (so far). Needs to start human trials some time, which is where about 95% of promising drugs in development fall over.
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