by Darrell K. Sweet (American illustrator, 1934-2011) Cover illustration for "The Unforsaken Hiero" novel by Sterling E. Lanier, Ballantine/Del Rey Books, 1983 Also known as "Delicate Negociations" #12 Card in FPG Darrell K. Sweet Fantasy Art Trading Cards, 1994
**Megatrend #12** - Personalized, Precision Medicine: "Tomorrow's cure lies not in a universal pill, but within our own genetic code." - Futurist Jim Carroll
---
(Futurist Jim Carroll is writing a series on 30 Megatrends, which he first outlined in his book Dancing in the Rain: How Bold Leaders Grow Stronger in Stormy Times. The trends were shared in the book as a way of demonstrating that, despite any period of economic volatility, there is always long-term opportunity to be found. The book is now in print - learn more at dancing.jimcarroll.com)
---
The one-size-fits-all era in medicine is ending. Treatments, nutrition, and wellness approaches tailored to individual genetic profiles are becoming the standard, not the exception. As with every post in this series, there's a PDF here that goes into more depth on this trend.
There's a little bit of duplication with some of the material covered in previous megatrends with this one, but it's important ot note that this trend is powerful enough on its own to deserve its own post.
What's it all about? We are combining what we might call 'next-generation genomic sequencing', AI, and CRISPR gene editing, to come up with a new health paradigm that involves 'fixing people before they are sick rather than after.' Why these 3 trends? The cost for genomic sequencing is collapsing, AI is accelerating the ability to do so, and gene editing allows us to correct the genetic causes of disease at the source.
Before going further, it's important to define the revolution by understanding two key terms.
The first is Personalized Medicine, which uses an individual's unique genomic, environmental, and lifestyle information to guide decisions for prevention, diagnosis, and treatment of disease. It's based on the idea that because no two individuals are the same, they should not receive the same healthcare.
The second term is Precision Medicine. While often used interchangeably, it more accurately describes the strategy of stratifying individuals into small populations based on shared characteristics. It focuses on identifying which healthcare and pharmaceutical approaches will be most effective for those small, specific groups of people, rather than creating unique treatments for each individual.
While its potential is immense, the transition to personalized medicine is not merely a technological upgrade but a disruptive force that challenges the foundational structures of healthcare delivery, research, and regulation.
Even so, over the long term, it's one of the biggest megatrend opportunities of our time.
Devlog #12: Few advancements this weekend (the cold is killing me) but there's a basic card creator that I'm working on, although almost in the dark because I really don't want to touch javascript
Trains #11 and #12 are more trams. Train #13 is this handsome, modern EMU from Zagreb to Volinja (and return to Sunja) pictured here at Volinja. I'd have liked to have gone further and crossed the border into Bosnia-Herzegovina, but guess what? There aren't any trains. No #crossborderrail for me @jon. The onward line across the river Una to Bosnia is on the left beyond the train.
The ispace RESILIENCE lunar lander successfully completed a flyby of the Moon reaching its closest point at 8,400 km altitude on Feb 14 at 22:43 UTC.
Unlike the Firefly mission, RESILIENCE will continue to travel ~1.1 million km out before looping back towards the Moon for lunar orbit insertion, in early May. See post #12 for the orbit diagram.
(gdb) bt #0 0x000055be176f0023 in findHashedClass ( classname=classname@entry=0x7ffe18d975b0 "java/lang/Class", class_loader=class_loader@entry=0x7f44946c5d00) at class.c:1277 #1 0x000055be176f16f4 in findNonArrayClassFromClassLoader ( classname=0x7ffe18d975b0 "java/lang/Class", loader=0x7f44946c5d00) at class.c:1367 #2 0x000055be176f1a4e in createArrayClass ( classname=classname@entry=0x55be56e68560 "[Ljava/lang/Class;", class_loader=0x7f44946c5d00, class_loader@entry=0x7f44946c5da0) at class.c:608 #3 0x000055be176f1b60 in findArrayClassFromClassLoader ( classname=0x55be56e68560 "[Ljava/lang/Class;", class_loader=0x7f44946c5da0) at class.c:1317 #4 findArrayClassFromClassLoader (classname=0x55be56e68560 "[Ljava/lang/Class;", class_loader=0x7f44946c5da0) at class.c:1313 #5 0x000055be1770407f in executeJava () at interp.c:2127 #6 0x000055be176f43d3 in executeMethodVaList (ob=0x0, class=0x7f44949f95e8, mb=0x55be56e56fb0, jargs=jargs@entry=0x7ffe18d97750) at execute.c:101 #7 0x000055be176f457f in executeMethodArgs (ob=ob@entry=0x0, class=class@entry=0x7f44949f95e8, mb=<optimized out>) at execute.c:73 #8 0x000055be176f1430 in initClass (class=0x7f44949f95e8) at class.c:1160 #9 0x000055be176fe280 in resolveMethod (class=<optimized out>, cp_index=<optimized out>) at resolve.c:192 #10 0x000055be17703a39 in executeJava () at interp.c:1580 #11 0x000055be176f43d3 in executeMethodVaList (ob=0x0, class=0x7f44949f2f40, mb=0x55be56e4ee70, jargs=jargs@entry=0x7ffe18d979b0) at execute.c:101 #12 0x000055be176f457f in executeMethodArgs (ob=ob@entry=0x0, class=class@entry=0x7f44949f2f40, mb=mb@entry=0x55be56e4ee70) at execute.c:73 #13 0x000055be176ea7f9 in main (argc=10, argv=0x7ffe18d97c98) at jam.c:350