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   Flick ?? (flick@spinster.xyz)'s status on Monday, 23-Oct-2023 13:58:30 JST Flick ??

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   • Matron of the ninth circle

   Talk to me about monoclonal antibodies vs NSAIDs for arthritis, anyone who knows?

   @polarisera @GrumpyOldNurse @Raunchel

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     @polarisera reposted your post (polarisera@spinster.xyz)'s status on Monday, 23-Oct-2023 13:58:29 JST @polarisera reposted your post

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     • Feart n Tired ???????
     • Matron of the ninth circle
     @GrumpyOldNurse @FeartnTired @Flick I've not read much (other than induced arthritis from vaccine injury). In the autoimmune version, we need to tell the body to stand-down, so I would guess we'd need monoclonal anti-antibodies. We can induce all sorts of permanent sensitivities by serum transfer (poor tortured animals), but we can hardly turn it off. It's a sad one-way street (so far). Whoever figures out how to turn off induced allergies and sensitives without wrecking the entire immune response will be the greatest scientist(s) of all time. There is a far bigger riddle there than our current crop of toadies can imagine.
     
     A long time ago I read a strange study where they took terminally ill subjects who happened to also have arthritis (donating their bodies to science, and I don't remember if RA, or just osteo). They gave the treatment group fish oil, then when they died and examined all their bones, the study showed joint lubrication in the treatment group above the control. This was a very small n, as you can imagine. Very rarely do we get this sort of postmortem control studies (but we do all the time in animals, as we kill them afterwards for our betterment and to thank them for their service)
     
     If you want horror photos to post outside for Halloween, just look at the induced allergy studies in animals. The kids will never come back.
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     @polarisera reposted your post (polarisera@spinster.xyz)'s status on Monday, 23-Oct-2023 13:58:29 JST @polarisera reposted your post

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     • @polarisera reposted your post
     • Feart n Tired ???????
     • Matron of the ninth circle
     @GrumpyOldNurse @FeartnTired @Flick I was just reading about Gremlin-1, notch/stem cell and other voodoo signaling an shepherding and the possibility of truly healing arthritis, not just slowing it. Since the complex self/notself systems are involved I don't expect any progress until the medieval vaccine cult is deposed.
     
     https://atm.amegroups.org/article/view/91401/html
     Seahorses are horses likes this.
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     Feart n Tired ??????? (feartntired@spinster.xyz)'s status on Monday, 23-Oct-2023 13:58:30 JST Feart n Tired ???????

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     • @polarisera reposted your post
     • Matron of the ninth circle
     @Flick @polarisera @GrumpyOldNurse if it's autoimmune the MABs may help. if it's osteoarthritis they won't.
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     Matron of the ninth circle (grumpyoldnurse@spinster.xyz)'s status on Monday, 23-Oct-2023 13:58:30 JST Matron of the ninth circle

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     • @polarisera reposted your post
     • Feart n Tired ???????
     @FeartnTired @Flick @polarisera What Feart said.