@GrumpyOldNurse @FeartnTired @Flick I've not read much (other than induced arthritis from vaccine injury). In the autoimmune version, we need to tell the body to stand-down, so I would guess we'd need monoclonal anti-antibodies. We can induce all sorts of permanent sensitivities by serum transfer (poor tortured animals), but we can hardly turn it off. It's a sad one-way street (so far). Whoever figures out how to turn off induced allergies and sensitives without wrecking the entire immune response will be the greatest scientist(s) of all time. There is a far bigger riddle there than our current crop of toadies can imagine.

A long time ago I read a strange study where they took terminally ill subjects who happened to also have arthritis (donating their bodies to science, and I don't remember if RA, or just osteo). They gave the treatment group fish oil, then when they died and examined all their bones, the study showed joint lubrication in the treatment group above the control. This was a very small n, as you can imagine. Very rarely do we get this sort of postmortem control studies (but we do all the time in animals, as we kill them afterwards for our betterment and to thank them for their service)

If you want horror photos to post outside for Halloween, just look at the induced allergy studies in animals. The kids will never come back.