@binkle The answer is yes. You'd get a spike in serum estrogen levels as fat is used. Same for xenoestrogens. Fat itself is an estrogen producer though, so it would be a transient phase ultimately leading to less estrogen. The most impactful time for this IMO would be early puberty where a lot of boys out on weight before leaning out. If they're eating shitty foods and exposed to a lot of xenoestrogens or even real estrogen from environmentals, they'll shed a lot of fat (hopefully) and possibly flush that into their system during that same time. I don't know how impactful that actually is, but it might explain the rise in gyno and pseudogyno. We might need some more Peatpilled bros to correct me. @Xenophon any ideas?