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- Embed this noticeThe problem with willow bark is that it is far harsher on the gastrointestinal tract than aspirin, which can itself be pretty bad.
A better example of a retarded drug is Vayarin. It's basically just a phosphatidylserine bound to omega-3 with epa added. The PS-O3 molecule just breaks into PS and O3 in the body. They created the drug after it was discovered that this combination of fatty acids could aid nutritional deficiencies and cellular repair to lessen the effects of adhd. They claim you can't get the same effect by taking PS, O3, and EPA alone, which they know is bullshit, because the studies show otherwise. They also claim their brand is a specially balanced brand.
Nonetheless, changing a molecule isn't as easy as it sounds. It can competely change the effect, or cause the substance to have no effect at all.
The main wall is really the cost of getting FDA approval, which is usually only worth it if you have the exclusive right to produce. Without it, the substance can't be prescribed, nor can it be advertised as curing a disease, and for that reason, generally isn't a competitor. Natural supplements fall into this category.
The next step is to attack any claims that a natural substance can have an effect by influencing discussions and questioning the effectiveness or quality of supplements, generally, this includes spreading theories like "if it worked, someone would find a way to patent it." Basically, you've bought big pharma's propoganda and are repeating it. Qui bono?