@futurebird I work in tech, not physics or more classical engineering, but I can say that the number of times I've wished staff knew calculus when they didn't? Zero in twenty years. The number of times I've wished they knew basic statistics when they didn't? At least once a month, for twenty years. @whknott
The RNA technology that was used to develop most of the covid vaccines is driving an absolute revolution in medicine right now. A vaccine for malaria, the disease that has killed more people than anything else in history. Personalized vaccines for cancers — the list goes on and we're just getting started. Much of this development is locked up in commercial pharma companies — there are papers, of course but replicating them in practice, let alone continuing development, is very hard without active access to the team involved. It's also very expensive. A lot of that development money comes from the US government. Now, yes it's a problem that that funding is going to private companies that are ransoming patients for their life savings in exchange for life-saving medicine, but this is as much a regulatory problem as it is a structural one. As long as those teams exist, the possibilities of these tools exist also.
Having an American government that wants to actively dismantle vaccine-related research and eliminate its funding is an existential threat to humanity:
I wish Signal had per-chat settings for read receipts and typing indicators, plus global defaults for new chats (and a way to reset everything to the defaults, ideally showing a list of what would be changed).
There's a ton of really useful work to be done around harm reduction in many many different health contexts, and there is absolutely a bunch of stuff that you can do with any skillset — even more if you have some money to throw around — to help out. Listen to the people actually affected and the people already helping them, and do what they say will help!
Yes, you likely won't get a lot of adulation for this, but you will make a real difference.
If you want to make medication yourself and/or suggest that other people not already in the business do so, you need to a) figure out how to prove *for each dose* that whatever substance is produced doesn't have anything else bad in it, and b) will be effective and at the expected dosage, and c) what degree of certainty you've done and and b to. You should probably also prove d) what the expected shelf life is, but a, b, and c are the absolute minimum. They are also significantly harder than making a substance.
If you have no plans for a, b, and c, you're not doing anything that should be described as making medication.
@jollyorc Yeah no it's entirely unreasonable. On the other hand, 1ms latency audio everywhere in the house that's (almost) as reliable as a wire. @akareilly
@jollyorc @akareilly I'll go HA once Hue is broken, but not before — I was going to have to do it to get integration with the DMX side, but now that I'm moving to MA3, I can just write Lua against the hue API library, which is actually going to be better in the end when it comes to representing what the hues can actually do.
I just chucked my Sonos pair because they were irretrievably shit. I can't actually recommend buying an Allen & Heath SQ6, the Dante card, and eight two channel Audinate Dante dongles to anyone who isn't either insane or actually running a venue, but it has solved that problem in a sufficiently final way. Of course, I still have a Wiim box hooked up to all that to get audio in 🤣
@jollyorc Yes, but afaik they're all still third party, which means intentional compatibility issues from the Hue side. Also, in my particular weird-ass use case I need to be able to lock out all the lights witches every time we have a party, so if switched to those, I'd also have to move to home assistant — at least the annoying come off the wall switches let me just take them all and shove them in a drawer. @akareilly
@nonlinear Building these systems isn't really my hobby, so I'm buying on the basis of software stack quality and reliability alone, which has meant nothing but Hue. I'm aware that at some point I'll be forced to replace all five bridges with a couple of home assistant installs, but this side of the house has already taken an order of magnitude more time than the professional side, so I'm really uninterested in sysadmining it harder. Otoh, the professional gear takes six weeks to get and costs a grand or more a fixture, while I can buy Hue bulbs at the hardware store.
The hardware layer won't get less crap until the business model/consumer expectations change, and thus the only real place for usability improvements is at the software layer, aka where the enshitification is happening. @akareilly
Thinking about security, failure, change, art, and living. Recruiting barbarians; complicate your narratives. Fractional CISO to startups via Systems Structure Ltd. HEL/NYC/LON