Used SSRIs for much of the last twenty-five years (off for almost two years now). If you want/need comfortable indifference to much of existence, it's zen in a bottle, but being a chemically-induced, long- term life experience, I'd say it might be best to work shit out on your own, if you have the strength (I didn't)... Long-term effects seem to be mixed... Don't regret using, but the indifference to much is real... Was mentally overcharged before, now rather bland but often comfortable... Results may vary...