@RL_Dane Yes, you can use flashrom, which is in OpenBSD ports, or compile the newer flashprog.
To use flashrom/flashprog, first you boot boot OpenBSD with kern.securelevel=-1
See: https://man.openbsd.org/securelevel
Libreboot recommends flashprog these days, which is a modern fork of flashrom lead by Nico Huber, though you can still use flashrom if you wish.