@LiberalEd @ElleGray Chloroform and ether, inhaled, are pretty famous for their nausea. After doing a little more reading, it looks like chloroform might have actually had some cough suppression effects. One Night was one of many syrups using it, and CNS inhibition is a common old timey way to suppress cough. And it wasn't formally banned until 1975!
This might be like using strychnine for performance enhancement...little bit will do what you want but the line of overdose is a fine one.