This long blog post essay by Aria (@woof) is an encapsulation of all of the madness of the last three years of the Masto Fediverse re: the FediHOA and its crusade against trans folk and Indy Leftists. It is more than worth a read.
https://aria.dog/barks/ethics-in-transgenderism/
My experience with the FediHOA was more tangent (defending a cyberfriend who was targeted), but it is still, having felt a glancing blow rather than the full assault, it's worthy of caution. Also, self-hosting is indeed BASED.