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   CJ Bellwether (siege@octodon.social)'s status on Wednesday, 25-Dec-2024 04:09:55 JST CJ Bellwether

   in reply to

   • masukomi
   • Emmy - Dial Tone *biiiiip*

   @masukomi @sillyCoelophysis

   poll of transfem people taking Progesterone regarding sex drive:

   https://octodon.social/@siege/110441708843689395

   testosterone is not the only hormone that influences sex drive - estrogen certainly does, theres no reason to assume progesterone doesnt except ongoing association that women dont naturally have sex drives / sex is a masculine urge.

   How quickly youll feel any effect definitely depends on how you're taking it. Orally you'll notice some effects within half an hour since its metabolites act as a sedative. However that will be nullified if you're taking a blocker like finasteride (that will prevent the prog from breaking down to allo).

   • Embed this notice
     masukomi (masukomi@connectified.com)'s status on Wednesday, 25-Dec-2024 04:09:59 JST masukomi

     in reply to

     • Emmy - Dial Tone *biiiiip*

     @sillyCoelophysis @siege

     re how quickly they have effect:

     Some effects of HRT are noticeable quickly (like Spironolactone's ) some just slide in subtly. I don't think it really matters because physical transition from HRT is a multi-year process.

     In that context, does it really matter if it was a day or a week or a month before you could see effects?

   • Embed this notice
     masukomi (masukomi@connectified.com)'s status on Wednesday, 25-Dec-2024 04:10:05 JST masukomi

     in reply to

     • Emmy - Dial Tone *biiiiip*

     @sillyCoelophysis @siege

     Depression makes sense but not because of the drug so much as because trans tend to feel emotionally better when they've got a hormone balance that better aligns with their inner self.

     Spironolactone alleviates a significant source of my body dysphoria which makes me feel better, which makes me less unhappy. but it's not because removing depression is a side-effect of spiro.

   • Embed this notice
     masukomi (masukomi@connectified.com)'s status on Wednesday, 25-Dec-2024 04:10:11 JST masukomi

     • Emmy - Dial Tone *biiiiip*

     @sillyCoelophysis @siege

     i am _extremely_ suspicious of those extra benefits.

     it has zero noticeable effect on my ADHD.

     It has done nothing to improve my sleep. if anything it might make it worse because upset stomach is a frequent side-effect (and thus why you're instructed to take it before bed)

     Increased sex drive makes ZERO sense because if it has ANY anti-androgen properties you'd (by definition) have LESS sex drive.

     can't comment on anxiety.