Yeah, this is really important to realise. It is always okay to block or mute for any reason! It isn't an offensive thing to do on here!
It's just a choice of what you want to see, and it isn't necessarily any kind of comment on the objective value of the account you block.
(I guess only exception would be some kind of public body, they shouldn't really be blocking their own citizens. But those kinds of accounts are only a tiny minority.)