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Here we see the cherry-picked NM#93 sample used to inoculate the mice. 7.13~7.33 log10 TCID50/ml may not mean anything to most people, but these numbers are very low in all reality. It's present but it should be made clear that the infection in the host cows is not severe. For comparison, antibody levels in milk from cows that have survived the infection (they all survive influenza, effectively) are typically in the range of five to ten times the detected levels we see here, and sometimes as high as fifty times especially immediately after infection. https://www.frontiersin.org/articles/10.3389/fnut.2018.00052/full

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Here we see the cherry-picked NM#93 sample used to inoculate the mice. 7.13~7.33 log10 TCID50/ml may not mean anything to most people, but these numbers are very low in all reality. It's present but it should be made clear that the infection in the host cows is not severe. For comparison, antibody levels in milk from cows that have survived the infection (they all survive influenza, effectively) are typically in the range of five to ten times the detected levels we see here, and sometimes as high as fifty times especially immediately after infection. https://www.frontiersin.org/articles/10.3389/fnut.2018.00052/full
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fluffy@baraag.net's status on Monday, 27-May-2024 03:49:27 JST fluffy
in reply to

@jeffcliff @sun
https://www.nejm.org/doi/full/10.1056/NEJMc2405495
Let's take a look at this very early research.
Well, as I see it these methods are very flawed.
Allow me to explain my concerns.
https://link.springer.com/article/10.1007/s12250-020-00230-5
The measurement of 7.33 log10 TCID50/ml is incredibly odd, it's basically at the limits of detection, I have no idea why they'd use the log10 range unless it was to skew results.
It's clear that they isolated the virus from the samples before the mice experiment.
Also, it proves intentional spread.

In conversation about a year ago from baraag.net permalink