Get a Glock, M&P, CZ P-series, or any other modern defense orient handgun, cock the striker, throw it on the ground until the striker lets go, and get back to me. I won't hold my breath.
If you don't carry with a round in the chamber, you're a fool. An attacker isn't going to respect your request to halt for a moment so you can chamber a round.
Chambering a round is easy in a flat range. It's a whole other thing when somebody is beating on you.