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Notices by Brad Mitchell (brad@zeroes.ca), page 2

  1. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Friday, 24-Nov-2023 13:11:34 JST Brad Mitchell Brad Mitchell

    November 22, 2023-“Importantly, there seems to be a poor relationship between the severity of COVID symptoms and the risk of Long COVID”“.. 70% of children who had LC, they were considered medium or severe. This implies that the symptoms may have a considerable impact on daily life” “Unfortunately, as SARS-CoV-2 has spread, it is now near impossible to find an unexposed group for comparison” - https://journals.lww.com/pidj/fulltext/9900/long_covid_in_icelandic_children__a_matched_cohort.651.aspx

    In conversation Friday, 24-Nov-2023 13:11:34 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: images.journals.lww.com
      Long COVID in Icelandic Children: A Matched Cohort Study of ... : The Pediatric Infectious Disease Journal
      onse rates have been few. Methods: We obtained identifiers for all 837 Icelandic children diagnosed with SARS-CoV-2 by PCR between March 2020 and June 2021 and contacted them by telephone. We asked about 10 physical and mental symptoms being present at least twice weekly for at least 2 months. Participants who reported symptoms were contacted again a year later. For each subject who completed the questionnaire, an age- and sex-matched comparator without SARS-CoV-2 infection was asked to complete the same questionnaire, and the risk difference was calculated. Results: Responses from 643 cases and 602 comparators were analyzed. Children who had been infected with SARS-CoV-2 were more likely to report one or more symptoms, except for anxiety/depression and sleep disturbances. Fatigue and loss of concentration were evidently more common in cases among teenagers (risk difference: 15%; 95% CI: 7–22% and 15%; 95% CI: 7–23%, respectively). At the second follow-up, close to a third of Long COVID cases had resolved but some participants had developed new persistent symptoms. Conclusion: Symptoms of Long COVID in children are common and impact their quality of life. The importance of further unraveling the pathophysiology of acute and long-term symptoms following SARS-CoV-2 infection in children is vital as well as potential preventive measures....
  2. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Wednesday, 15-Nov-2023 19:43:55 JST Brad Mitchell Brad Mitchell

    November 15, 2023- “ In this study, we aimed to reveal the clinical features of the SARS-CoV-2 omicron variants among children, and revealed that, in comparison with other SARS-CoV-2 variants, the omicron variant was associated with more clinical symptoms, particularly seizures. The number of children with seizures and unconsciousness was significantly higher after than before the emergence of the SARS-CoV-2 omicron variant.”- https://www.frontiersin.org/articles/10.3389/fped.2023.1273464

    In conversation Wednesday, 15-Nov-2023 19:43:55 JST from zeroes.ca permalink

    Attachments


  3. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Monday, 13-Nov-2023 13:09:40 JST Brad Mitchell Brad Mitchell

    Published November 7, 2023- Persistent cognitive slowing in post-COVID: longitudinal study over 6 months; showed cognitive slowing indicated by longer reaction times compared to control participants (r = 0.51, p < 0.001) in a simple-response tonic alertness task- https://link.springer.com/article/10.1007/s00415-023-12069-3

    In conversation Monday, 13-Nov-2023 13:09:40 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: media.springernature.com
      Persistent cognitive slowing in post-COVID patients: longitudinal study over 6 months - Journal of Neurology
      from Finke, Kathrin
      Background Fatigue is a frequent and one of the most debilitating symptoms in post-COVID syndrome (PCS). Recently, we proposed that fatigue is caused by hypoactivity of the brain’s arousal network and reflected by a reduction of cognitive processing speed. However, it is unclear whether cognitive slowing is revealed by standard neuropsychological tests, represents a selective deficit, and how it develops over time. Objectives This prospective study assesses whether PCS patients show deficits particularly in tests relying on processing speed and provides the first longitudinal assessment focusing on processing speed in PCS patients. Methods Eighty-eight PCS patients with cognitive complaints and 50 matched healthy controls underwent neuropsychological assessment. Seventy-seven patients were subsequently assessed at 6-month follow-up. The Test for Attentional Performance measured tonic alertness as primary study outcome and additional attentional functions. The Neuropsychological Assessment Battery evaluated all key cognitive domains. Results Patients showed cognitive slowing indicated by longer reaction times compared to control participants (r = 0.51, p 
  4. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Friday, 03-Nov-2023 09:26:18 JST Brad Mitchell Brad Mitchell
    in reply to

    -So, with Long Covid.. Do we ever really “clear” the virus?🤷♂️ "We detected replication-competent SARS-CoV-2 in bronchoalveolar fluid (BALF) Mac for up to 18 months after infection." Related? "Due to their long life span and ability to reside in virtually every tissue, macrophages have been proposed to play a critical role in the establishment and persistence of the HIV-1 reservoir."- https://www.frontiersin.org/articles/10.3389/fmicb.2019.02828/full

    In conversation Friday, 03-Nov-2023 09:26:18 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: www.frontiersin.org
      The Role of Macrophages in HIV-1 Persistence and Pathogenesis
      Current antiretroviral therapy (ART) effectively suppresses Human Immunodeficiency Virus type 1 (HIV-1) in infected individuals. However, even long term ART does not eradicate HIV-1 infected cells and the virus persists in cellular reservoirs. Beside memory CD4+ T cells, cells of the myeloid lineage, especially macrophages, are believed to be an important sanctuary for HIV-1. Monocytes and macrophages are key players in the innate immune response to pathogens and are recruited to sites of infection and inflammation. Due to their long life span and ability to reside in virtually every tissue, macrophages have been proposed to play a critical role in the establishment and persistence of the HIV-1 reservoir. Current HIV-1 cure strategies mainly focus on the concept of “shock and kill” to purge the viral reservoir. This approach aims to reactivate viral protein production in latently infected cells, which subsequently are eliminated as a consequence of viral replication, or recognized and killed by the immune system. Macrophage susceptibility to HIV-1 infection is dependent on the local microenvironment, suggesting that molecular pathways directing differentiation and polarization are involved. Current latency reversing agents (LRA) are mainly designed to reactivate the HIV-1 provirus in CD4+ T cells, while their ability to abolish viral latency in macrophages is largely unknown. Moreover, the resistance of macrophages to HIV-1 mediated kill and the presence of infected macrop...
  5. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Friday, 03-Nov-2023 09:18:05 JST Brad Mitchell Brad Mitchell

    Welp. 🤷♂️ Next time you hear “I tested negative so it’s definitely not Covid” Published November 2, 2023-“In this study, using Wuhan or Omicron variants of SARS-CoV-2, we detected viral RNA in BALF of 17 of 25 infected macaques and viral antigens in the BALF Mac of 20 of 25 macaques at 6 months p.i., with the virus in the BALF Mac capable of replication up to at least 221 d p.i., even when it was undetectable in nasopharyngeal and tracheal swabs”- https://www.nature.com/articles/s41590-023-01661-4

    In conversation Friday, 03-Nov-2023 09:18:05 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: media.springernature.com
      SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells - Nature Immunology
      from Müller-Trutwin, Michaela
      Huot et al. show that interferon-γ (IFN-γ) regulates the persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in bronchoalveolar macrophages from cynomolgus macaques up to 18 months postinfection.
  6. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Tuesday, 31-Oct-2023 01:33:27 JST Brad Mitchell Brad Mitchell

    October 26, 2023- (although we’ve known this since 2020) “SIDE EFFECT Children infected with Covid at risk of blood vessel damage that can trigger clots, scientists warn” - https://www.thesun.co.uk/health/24519378/blood-vessel-damage-children/

    In conversation Tuesday, 31-Oct-2023 01:33:27 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: www.thesun.co.uk
      Children with Covid at risk of blood vessel damage that 'can trigger clots'
      from 161385360554578
      VIRTUALLY all children infected with Covid suffer from serious blood vessel damage, scientists have warned. The US study found a “high proportion” of kids with the bug had elevated levels of …
  7. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Tuesday, 31-Oct-2023 01:33:25 JST Brad Mitchell Brad Mitchell
    in reply to
    • trendle.55 :signal:

    @trendless Why do you suppose they are letting mainstream people know now, after so much damage has been caused and literally years have gone by? Did someone miss a hush payment or something? - https://www.mirror.co.uk/news/health/parents-issued-grim-health-warning-31285897

    In conversation Tuesday, 31-Oct-2023 01:33:25 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: i2-prod.mirror.co.uk
      Grim health warning for any children who test positive for Covid
      from https://www.mirror.co.uk/authors/monica-charsley/
      Scientists have revealed another side effect of Covid-19 which can mainly effect children and teenagers - it comes after they launched a study to see the impact the bug had on cardiovascular health
  8. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Wednesday, 25-Oct-2023 14:19:09 JST Brad Mitchell Brad Mitchell

    “Deaths from all diseases by month in the 18-44 year old demographic in the USA”

    “Red shaded areas are where deaths exceed expected ("excess deaths") based on 2013-2019 baseline.” - Gregory Travis (10/24/23)

    In conversation Wednesday, 25-Oct-2023 14:19:09 JST from zeroes.ca permalink

    Attachments


    1. https://media.zeroes.ca/media_attachments/files/111/293/511/168/530/669/original/0a051f35a769d199.png
  9. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Saturday, 14-Oct-2023 15:32:43 JST Brad Mitchell Brad Mitchell

    October 13, 2023- “Viral levels in wastewater are similar to what they were during the first two waves of the pandemic.” - https://www.thenation.com/article/society/covid-pandemic-panic-calm-advice/

    In conversation Saturday, 14-Oct-2023 15:32:43 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: www.thenation.com
      The Coronavirus Still Doesn’t Care About Your Feelings
      from https://www.thenation.com/authors
      The Covid-19 pandemic is not a state of mind—and telling us not to panic isn’t healthcare.
  10. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Sunday, 08-Oct-2023 09:24:55 JST Brad Mitchell Brad Mitchell

    Published Sept. 21, 2023 “The majority of cases of long COVID in health-care workers were detected in employees who had been infected with the virus since the emergence of the Omicron variant, who had been vaccinated, and whose state of health had not required hospitalisation.” - https://montreal.ctvnews.ca/up-to-10-per-cent-of-quebec-health-care-workers-affected-with-long-covid-1.6571752

    In conversation Sunday, 08-Oct-2023 09:24:55 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: www.ctvnews.ca
      Up to 10 per cent of Quebec health-care workers affected with long COVID
      from @CTVMontreal
      Between six and 10 per cent of health-care workers in Quebec have suffered from the long COVID since the start of the pandemic, preliminary data released on Thursday revealed at the first Canadian Symposium on long COVID, in Montreal.
  11. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Monday, 02-Oct-2023 09:34:09 JST Brad Mitchell Brad Mitchell

    Weird that it’s not that “mystery illness” that’s been going around 🤷♂️ - https://www.standard.co.uk/news/london/gatwick-flights-cancelled-air-traffic-control-staff-covid-b1109299.html

    In conversation Monday, 02-Oct-2023 09:34:09 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: static.standard.co.uk
      Gatwick airport cancels 160 flights amid air traffic control staff sickness
      from Sami Quadri, Josh Salisbury, Miriam Burrell
      Gatwick Airport limits number of flights over the rest of the week after shortage of air traffic control staff
  12. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Monday, 02-Oct-2023 09:34:08 JST Brad Mitchell Brad Mitchell
    in reply to

    You know, .. the “MYSTERY ILLNESS” that’s been going around 🤷♂️? https://www.wsws.org/en/articles/2023/09/24/uhyn-s24.html

    In conversation Monday, 02-Oct-2023 09:34:08 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: www.wsws.org
      COVID-19 rampant among musicians despite “end of the pandemic”
      Considering the enormous sums of money dependent on the public’s continuing to attend concerts, a pressure exists, on individual musicians and on promoters, to avoid associating such events with COVID. 
  13. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Monday, 02-Oct-2023 09:34:01 JST Brad Mitchell Brad Mitchell

    Citizens Public Service Announcement- It’s not seasonal, despite what you’re been told. “Covid-19 cases and hospitalizations have been on the rise in the Greater Boston area since mid-July.” - https://www.thecrimson.com/article/2023/9/19/fall-2023-covid-uptick/

    In conversation Monday, 02-Oct-2023 09:34:01 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: s3.amazonaws.com
      Harvard Students Report Surge in Covid-19 Cases with Fall Semester Underway | News | The Harvard Crimson
      Most freshmen arrive at Harvard College eager to participate in orientation activities, from wilderness hikes to leadership training. But this fall, some spent their first few days on campus in isolation amid a spike in Covid-19 infections.
  14. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Monday, 02-Oct-2023 09:33:59 JST Brad Mitchell Brad Mitchell
    in reply to

    Related-

    In conversation Monday, 02-Oct-2023 09:33:59 JST from zeroes.ca permalink

    Attachments


    1. https://media.zeroes.ca/media_attachments/files/111/100/228/318/520/138/original/ebc5efbd6a791b38.png
  15. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Thursday, 21-Sep-2023 05:03:11 JST Brad Mitchell Brad Mitchell

    🤷♂️ I guess the pandemic is ove.. “breaking news” “US households will be able to order more free Covid-19 tests starting Monday”

    In conversation Thursday, 21-Sep-2023 05:03:11 JST from zeroes.ca permalink
  16. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Tuesday, 19-Sep-2023 07:41:43 JST Brad Mitchell Brad Mitchell

    Interesting- September 18, 2023 - “Covid vaccination after long covid may be linked to better outcomes.” “Sixteen cytokines and chemokines were significantly decreased after vaccination.” - https://www.cidrap.umn.edu/covid-19/covid-vaccination-after-long-covid-may-be-linked-better-outcomes

    In conversation Tuesday, 19-Sep-2023 07:41:43 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: www.cidrap.umn.edu
      COVID vaccination after long COVID may be linked to better outcomes
      Sixteen cytokines and chemokines were significantly decreased after vaccination.
  17. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Sunday, 17-Sep-2023 10:46:35 JST Brad Mitchell Brad Mitchell

    September 16, 2023 - Mainstream news “COVID levels are so high, they’re hovering near 2020’s initial peak, as the WHO urges those at high risk to take any booster they can get their hands on” - https://fortune.com/well/2023/09/16/united-states-covid-levels-approach-first-pandemic-peak-2020-who-urges-vaccination-boosters-high-risk/

    In conversation Sunday, 17-Sep-2023 10:46:35 JST from zeroes.ca permalink

    Attachments

    1. Domain not in remote thumbnail source whitelist: content.fortune.com
      COVID levels are so high, they're approaching 2020's initial peak, as the WHO urges those at high risk to take any booster they can get their hands on
      It’s yet another sign that while the official pandemic state may be over, the days of COVID are far from it.
  18. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Thursday, 07-Sep-2023 14:58:57 JST Brad Mitchell Brad Mitchell

    Interesting- Patient 42 had mild covid, recovered and died 230 days later of unrelated causes. Their autopsy showed that they had viral RNA in 10 areas of their brain. https://www.nature.com/articles/s41586-022-05542-y/figures/1

    In conversation Thursday, 07-Sep-2023 14:58:57 JST from zeroes.ca permalink

    Attachments

    1. No result found on File_thumbnail lookup.
      Fig. 1: Distribution, quantification and replication of SARS-CoV-2 across the human body and brain. | Nature
  19. Embed this notice
    Brad Mitchell (brad@zeroes.ca)'s status on Friday, 18-Aug-2023 14:44:06 JST Brad Mitchell Brad Mitchell

    The dismantling of COVID data has indeed made the virus disappear for many. 🙈🙉🙊However as expected by those of us watching in disbelief, WHO is investigating BA.2.86, a new COVID variant with more than 30 mutations in the spike protein. It was discovered in Israel on Sunday, then Denmark then today in the U.S., in Michigan. None of the cases are related which means the REAL number of cases is likely MUCH higher. Could be a game changer or maybe not. I guess we’ll FAFO as usual .🤷♂️🤞🏼

    In conversation Friday, 18-Aug-2023 14:44:06 JST from zeroes.ca permalink

    Attachments


    1. https://media.zeroes.ca/media_attachments/files/110/906/208/412/287/761/original/c1f6fe50ad12d697.png

    2. https://media.zeroes.ca/media_attachments/files/110/906/209/302/625/055/original/5fc17ebd380fe5bb.png

    3. https://media.zeroes.ca/media_attachments/files/110/906/753/774/196/899/original/8925c6aebdae40ca.png

    4. https://media.zeroes.ca/media_attachments/files/110/906/754/604/922/104/original/d9def4a11aa632ea.png
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    Brad Mitchell

    Brad Mitchell

    Not pretending to be an expert, just someone who is sharing hopefully credible information. Zero covid advocate, accepting the reality of the ongoing pandemic and adapting to it. Proud father of three extraordinary adult children. Strongly support LGBTQ+ 🏳️🌈🏳️⚧️ and #BLM Husband, musician, composer, activist. Los Angeles (Profile photo is of me and our German Shepherd looking at me in front of some recording equipment).

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