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@goatsarah my wife is on it too, and it has transformed her life (and mine by extension). She’s a pharmacist and was concerned about the need to keep increasing the dose as time goes by, so she takes it for a few days and then takes a break, sometimes up to a week. She’s been able to reduce the dose doing this, which is helpful when shortages are common. YMMV, she knows what she’s doing, ask someone who does if you want to experiment.