Yup.
Ulcers: no H2 blockers/PPIs/H. pylori antibiotics, "cure" was surgery
No SSRI antidepressants
Only 1st generation neuroleptics (antipsychotic meds) with horrible side-effects
No ACE inhibitors/ACE2 blockers (hypertension was a killer)
No Type II diabetes treatments except diet and insulin
And so on.
... I have a copy of the British National Formulary from 1988, and one from 2018. The 2018 edition is literally twice as thick.
1965 was in the pharmacology dark ages.