@TheBigLoder @magicalthinking there are so many things that can be causing issues. We decided to change so many things. The easiest way to test things would be to do something like the Framingham study where you have half the groups randomly assigned to follow dietary/etc protocol as close to 1950s as possible and follow them.

It is quite leaky, but would quickly (1-5 years) prove if something significant was in the whole package and allow a wide scientific basis to drill in.