There were a bunch of really funny ladies in the LA scene in the oughts and 2010s, jen kirkman, janet varney, and tig nitaro spring to mind (of course bamford came out of that scene too), but I think the whole comedy community caught brain rot in 2016. I know tig went clapter shortly after her "live" special blew up, haven't really kept up with anyone else. I can't think of too many comics in general who stayed funny through trump and the pandemic.