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@artemist For the record, because people always underestimate it, we're not talking about small effect sizes here:

It's almost universally a ~40% drop in all overdose related metrics, which translates to a ~30% drop in unintentional poisonings of any kind. UK reported a ~60% drop in overdose related liver transplants from mandating blister packs. 65% more effective in preventing child access to medication than "child resistant" pill bottles.