This is where one of Hamilton's statements stuck with me -- the assertion that such systems are software, hardware, and peopleware. And these three are distinct! You can't treat people like hardware, we operate in a stochastic and, frequently, incomprehensible way.
Hamilton wasn't saying that the error would happen, just that it had a chance of occurring, and therefore steps should be taken to minimize the likelihood. Precautionary measures, because while training is important, so is the setup of a system, and it should always be configured - physically or in software - to reduce the likelihood of a disaster as much as possible.
And definitely: people who are more at risk of Bad Things happening have fewer blind spots when it comes to those same Bad Things happening to someone else. We able-bodied people need, as a whole, to learn to start listening.