Yes and no. In a vacuum where you remove exposure to damaging substances you are still looking at generations of decline (studies have shown that giving fish a massive estrogenic dose 1 time causes increasing fertility loss as far as 3 or 4 generations down the road without any further exposure. They axed the study before more generations could be observed)
However there's plastic in the rain and EE2 in pretty much all of the water. So our exposure doesn't stop abruptly and is not a one time thing for many of the things destorying us.
Furthermore we struggle with tracking epigenetic markers and what they affect because of the mechanisms behind the process and the ridiculous timescales such research requires.
If the epigenome is affecting phenotype 3 generations down the road we are looking at very radical solutions to fix it which aren't just "sit and wait several generations without further exposure"
The epigenome continues to be inherited. To really counteract it, you should be prepared to adhere to a pretty strict breeding and early life conditioning process for a few generations. Dealing with the testosterone crisis, for example, is gonna be one hell of a nightmare.

Anyways, a single jab is still unacceptable in my book. All physical issues aside, it just shows you that the person is 100% part of the npc niggercattle mass and you shouldn't be breeding with those people. The mother's genetic contributions are very important to the quality of the offspring.
Unvaxxed is just the first checkmark.