Imagining an Abbott and Costello routine, where Abbott is neogender:
Costello: Are you a boy or a girl?
Abbott: No.
C: So what were you born as?
A: Yes.
C: No, I mean what is your sex?
A: Yes.
C: Your sex is yes?
A: No, my sex is what.
C: That's what I'm asking!
A: Yes.
C: What?
A: Yes.
C: Yes what?
A: Now you're catching on.
C: But do you have a penis or a vagina?
A: Yes.
C: Yes which?
A: No, yes what.
C: What?
A: Yes.
C: What's in your pants?
A: Yes.
C: Yes is in your pants?
A: No, what's in my pants.
C: That's what I'm asking!
A: Yes.
C: So who's asking?
A: No, what.
C: What?
A: Yes.
C: So what's in your pants?
A: Yes.
C: What's its name?
A: What.
C: The thing in your pants!
A: No, what's in my pants.
C: I'm the one asking you that!
A: You're the one asking what that.
C: What?
A: Yes.
C: So I'm asking "Yes" what's in your pants?
A: No, what's in my pants.
C: *throwing up his hands and resorting to shtick* Third base!
A: No, home is in my pants.
C: So you've got home in your pants?!
A: No, what's in my pants.
C: Home?
A: What.
C: Who?
A: No!
C: Third base!
A: Home!
C: What?!
A: Yes!
C: Fine, I give, I'll use whatever pronouns you want if you'll just stop.
A: Use "what."
C: *head explodes*
via @alice