@captainarcee While the landscape can shift from time to time, uBlock Origin (not lite) has worked for me so far and I've also had success with AdGuard AdBlocker on Chromium. I currently use Cromium to watch Youtube so AdGuard AdBlocker is the one I've used.
I also use NoScript but I don't think that can be used to block adds. I mean, you can but the adds would have to come from a source that can be disabled without breaking the page completely.