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Maija (maija@netzsphaere.xyz)'s status on Sunday, 06-Apr-2025 13:58:12 JST Maija
- Rusty Crab
@RustyCrab benzos

In conversation about 3 months ago from netzsphaere.xyz permalink
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  prettygood (prettygood@socially.drinkingatmy.computer)'s status on Sunday, 06-Apr-2025 13:58:11 JST prettygood
  in reply to
  - Rusty Crab
  @maija @RustyCrab literally safer than melatonin in my experience.
  
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  prettygood (prettygood@socially.drinkingatmy.computer)'s status on Sunday, 06-Apr-2025 14:03:14 JST prettygood
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  - Rusty Crab
  @maija @RustyCrab 2mg of melatonin destroys me worse than a liter of 80 proof liquor. I don't know why, but that shit hits me like a fucking cannonball. I would rather chase liquor with benadryl, the hangover would be easier to deal with.
  
  Xanax on the other hand is gentle and comfortable, much more pleasant and doesn't hang around for hours after you wake up.
  
  In conversation about 3 months ago permalink
  
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  Maija (maija@netzsphaere.xyz)'s status on Sunday, 06-Apr-2025 14:03:16 JST Maija
  in reply to
  - Rusty Crab
  - prettygood
  @prettygood @RustyCrab is that so? in what way? melatonin just doesnt work enough on me with my panic attacks and benadryl has too many consequences and sometimes doesnt work
  
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  Maija (maija@netzsphaere.xyz)'s status on Sunday, 06-Apr-2025 14:07:51 JST Maija
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  - Rusty Crab
  - prettygood
  @prettygood @RustyCrab interesting. melatonin doesn't do anythting to me butt make me a little more tired but that's not enough to get over my insomnia generalyl speaking
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 14:07:55 JST ✙ dcc :pedomustdie: :phear_slackware:
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  - Rusty Crab
  - prettygood
  @prettygood @RustyCrab @maija melatonin makes it imposible to go into rem sleep, aka you basically did not sleep.
  
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  prettygood (prettygood@socially.drinkingatmy.computer)'s status on Sunday, 06-Apr-2025 14:08:03 JST prettygood
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  - ✙ dcc :pedomustdie: :phear_slackware:
  - Rusty Crab
  @dcc @RustyCrab @maija is that fuckin why? That would explain a lot.
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 14:08:46 JST ✙ dcc :pedomustdie: :phear_slackware:
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  - Rusty Crab
  - prettygood
  @prettygood @RustyCrab @maija Yep, so if you know what real sleep is like then it is like staying up all night while also being uncomfortable.
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 15:14:21 JST sapphire
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  @dcc @RustyCrab @maija @prettygood I’m gonna need a source on this because I take 10mg a night to keep my sleep schedule regular and I have zero problems getting into REM
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 15:52:02 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood It works the same as caffeine in a sense (after you use it at the same amounts it does nothing) either its placebo or you are just going to sleep lol.
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 17:57:27 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood I think you did not read the first part of what i wrote, its like caffeine it stops working after you use the same amount for some time.
  
  In conversation about 3 months ago permalink
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 17:57:28 JST sapphire
  in reply to
  @dcc @RustyCrab @maija @prettygood so is it a placebo or does it completely remove your ability to enter REM sleep? It can’t be both
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:29:35 JST sapphire
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  @dcc @RustyCrab @maija @prettygood ok so how long am I getting absolutely destroyed on my basic bodily functions before it magically turns into a sugar pill bro?
  
  Do you a favor since you didn’t bother finding that source I asked for: I’ve been off mine for about 2 weeks and my Apple Watch does a pretty good job of measuring my sleep cycles accurately, I’ll get back to you with hard data in 48 hours or so.
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:29:35 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood > ok so how long am I getting absolutely destroyed on my basic bodily functions before it magically turns into a sugar pill bro?
  What
  >you didn’t bother finding that source I asked for:
  as far as i know there is no real study about metlation that matters
  >Apple Watch
  Not even close to accurate, i do have a study for that (i need to find it)
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:31:44 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood >I accept your concession,
  Is not, everyone i talk to who takes it reports the exact same shit.
  Also >watch on for two nights and bothering my girlfriend for hers
  Yea that was not hard to guess :alex_smile:
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:31:45 JST sapphire
  in reply to
  @dcc @RustyCrab @maija @prettygood >make an extreme claim
  >do you have any source for that
  >there is no source for that
  
  I accept your concession, thanks for saving me the trouble of sleeping with my watch on for two nights and bothering my girlfriend for hers
  
  In conversation about 3 months ago permalink
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:34:14 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood (that means everything you said is a lie and is basically useless )
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:34:55 JST ✙ dcc :pedomustdie: :phear_slackware:
  in reply to
  @sapphire @RustyCrab @maija @prettygood >have your magic sugar pill placebo resistance if it existed.
  The point is you can't measure sleep with fitness watches, so it does not really matter. Unless you have some better evidence other than "werks for me" nothing else here lol.
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:34:56 JST sapphire
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  @dcc @RustyCrab @maija @prettygood I don’t sleep with my watch on since I got the series 10 because the Milanese loop isn’t very comfortable in sleep. I was going to bother my girlfriend for her data because she takes melatonin nightly and would have your magic sugar pill placebo resistance if it existed.
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:37:05 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood I say i know about 5-7 people that all report similar issues.
  
  In conversation about 3 months ago permalink
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:37:06 JST sapphire
  in reply to
  @dcc @RustyCrab @maija @prettygood unless you’ve got better evidence than “doesn’t werk for vague others”
  
  In conversation about 3 months ago permalink
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:39:29 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood In fact in this very thread we have some one, i mean thats somewhat important.
  
  In conversation about 3 months ago permalink
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:55:01 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood > 4 wk.
  Not even close enough
  Also the reason why there is a "increase" is more likey to do with the fact they are in a study that says it will fix there problem
  Extra also >five women, nine men
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:55:02 JST sapphire
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  @dcc @RustyCrab @maija @prettygood I know a billion people who don’t therefore my anecdote is better.
  
  Off topic but: https://pmc.ncbi.nlm.nih.gov/articles/PMC10654909/
  
  The Apple Watch (series 8 which has less accurate sleep tracking than the Ultra and the series 10 which I’ve used) aren’t terribly accurate but they tend to skew data away from REM and deep sleep rather than toward it so would at least be good enough to disprove your retarded “melatonin doesn’t let you REM” claim
  In conversation about 3 months ago permalink
  Attachments
  1. Domain not in remote thumbnail source whitelist: cdn.ncbi.nlm.nih.gov
    
    Accuracy of 11 Wearable, Nearable, and Airable Consumer Sleep Trackers: Prospective Multicenter Validation Study
    
    Consumer sleep trackers (CSTs) have gained significant popularity because they enable individuals to conveniently monitor and analyze their sleep. However, limited studies have comprehensively validated the performance of widely used CSTs. Our study ...
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:55:02 JST sapphire
  in reply to
  @dcc @RustyCrab @maija @prettygood
  https://pubmed.ncbi.nlm.nih.gov/14715839/
  The results of the study show that melatonin was significantly more effective than placebo: patients on melatonin experienced significant increases in REM sleep percentage (baseline/melatonin, 14.7/17.8 vs. baseline/placebo, 14.3/12.0) and improvements in subjective measures of daytime dysfunction as well as clinical global impression score. Melatonin did not shift circadian phase or suppress temperature but did increase REM sleep continuity and promote decline in rectal temperature during sleep.
  
  Maybe you should start taking it so you can cool your ass down :)
  In conversation about 3 months ago permalink
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  1. Domain not in remote thumbnail source whitelist: cdn.ncbi.nlm.nih.gov
    
    Melatonin in patients with reduced REM sleep duration: two randomized controlled trials - PubMed
    
    Recent data suggest that melatonin may influence human physiology, including the sleep-wake cycle, in a time-dependent manner via the body's internal clock. Rapid-eye-movement (REM) sleep expression is strongly circadian modulated, and the impact of REM sleep on primary brain functions, metabolic pr …
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:56:41 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood > 14 day trials
  Even less time
  > eight
  >24
  Different age to
  You got to read before you start talking fren
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:56:42 JST sapphire
  in reply to
  @RustyCrab @dcc @maija @prettygood
  https://pmc.ncbi.nlm.nih.gov/articles/PMC1665336/
  During melatonin treatment, sleep in the first 8 h of the 16 h sleep opportunities was increased by 2 h. Sleep per 16 h was not significantly different and approached asymptotic values of 8.7 h in both conditions. The percentage of rapid eye movement (REM) sleep was not affected by melatonin, but the percentage of stage 2 sleep and sleep spindle activity increased, and the percentage of stage 3 sleep decreased. During the washout night, the melatonin-induced advance in sleep timing persisted, but was smaller than on the preceding treatment night and was consistent with the advance in the endogenous melatonin rhythm. These data demonstrate robust, direct sleep-facilitating and circadian effects of melatonin without concomitant changes in sleep duration, and support the use of melatonin in the treatment of sleep disorders in which the circadian melatonin rhythm is delayed relative to desired sleep time.
  In conversation about 3 months ago permalink
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  1. Domain not in remote thumbnail source whitelist: cdn.ncbi.nlm.nih.gov
    
    Melatonin advances the circadian timing of EEG sleep and directly facilitates sleep without altering its duration in extended sleep opportunities in humans
    
    The rhythm of plasma melatonin originating from the pineal gland and driven by the circadian pacemaker located in the suprachiasmatic nucleus is closely associated with the circadian (approximately 24 h) variation in sleep propensity and sleep ...
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 18:59:39 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood >stop criticizing my studies
  No i don't think i will, becuase you know why? study does not mean anything unless its right.
  >I’m going back to sleep
  I'm not :no_sleep: you can though.
  
  In conversation about 3 months ago permalink
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 18:59:40 JST sapphire
  in reply to
  @dcc @RustyCrab @maija @prettygood how about you stop criticizing my studies and find better ones. We’re now two studies and a medical journal, my personal experience and the personal experience of my girlfriend vs “source: your ass”
  
  Do better or I’m going back to sleep, you’re legitimately more boring than a 9 hour transatlantic flight
  
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  ✙ dcc :pedomustdie: :phear_slackware: (dcc@annihilation.social)'s status on Sunday, 06-Apr-2025 19:00:44 JST ✙ dcc :pedomustdie: :phear_slackware:
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  @sapphire @RustyCrab @maija @prettygood Well what ever you consider "sleep" to be
  
  In conversation about 3 months ago permalink
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  sapphire (sapphire@shortstacksran.ch)'s status on Sunday, 06-Apr-2025 19:00:45 JST sapphire
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  @dcc @RustyCrab @maija @prettygood I thought I couldn’t because melatonin fucked my REM
  
  In conversation about 3 months ago permalink
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  prettygood (prettygood@socially.drinkingatmy.computer)'s status on Monday, 07-Apr-2025 00:26:19 JST prettygood
  in reply to
  @sapphire @dcc @RustyCrab @maija my wife bought some canvas weave band for hers that she likes, which is noteworthy because she has texture autism about how things feel. I can ask her if you're looking for other options
  
  In conversation about 3 months ago permalink
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  sapphire (sapphire@shortstacksran.ch)'s status on Monday, 07-Apr-2025 00:43:39 JST sapphire
  in reply to
  @prettygood @dcc @RustyCrab @maija nah I don’t like wearing it to sleep anyway
  
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  sapphire (sapphire@shortstacksran.ch)'s status on Monday, 07-Apr-2025 00:52:25 JST sapphire
  in reply to
  @prettygood @RustyCrab @dcc @maija plus the Milanese loop looks good enough that my dad who hates technology complimented my watch and he was furious when I showed him it was a smartwatch
  
  In conversation about 3 months ago permalink
  
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