The famous terra cotta bust of Lorenzo. His flattened nose (broken in a brawl in his teen years) makes him look very different from his family, but its conspicuousness made it take a long time for us to notice he also has thickened bone development in his brows, cheekbones, and unusual jaw shape, and a tightened mouth consistent with muscle strain from overgrowth of the jawbone. Skeletal examination found evidence in his hands, his knees etc.
https://stockroom.wandering.shop/media_attachments/files/113/907/892/909/921/295/original/e9b536cfc91133f7.jpeg