No, we cannot claim that side effects cannot, 100% sure, ever happen after 2 months. Science does not do 100%. But, the evidence that it is extremely unlikely to happen is very strong after a phase 3 trial.
But, there is another aspect.
8/10
No, we cannot claim that side effects cannot, 100% sure, ever happen after 2 months. Science does not do 100%. But, the evidence that it is extremely unlikely to happen is very strong after a phase 3 trial.
But, there is another aspect.
8/10
There are no surpises. That inflammatory response is over within a few weeks. Side effects are mainly noted in the first 2-weeks, latest within 2 months. This is the reason, after lots of experience with vaccines, trials run for 2-3 months.
7/10
fever, feeling tired, nausea, etc. This includes other side effects from inflammatory responses such as myocarditis in more susceptible groups: males from the ages of puberty to about 40. ~4 days after vaccination.
So far, no surprises at all.
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(22)00059-5/fulltext
6/10
The only side effects are derived from that initial inflammatory reaction (RNA is short-lived). It is a short response. Some people are more sensitive to it, resulting in variable degrees of side effects: pain at the injection site, painful arm, swollen local lymph nodes,
5/10
Ah, but what about those negative consequences, those often claimed we do not know about, we cannot know about till we wait 3, 5, 10, 50, 100 years... a seemingly powerful argument against the new COVID-19 vaccines. However, this is not as strong argument as you may think.
4/10
Hence the long-term consequence of vaccination is the generation of antigen-specific memory B and T cells. These cells are very long lived, and will remain for many years to the rest of your life. They are the basis of your subsequent immune response against the same antigen
3/10
The vaccine caases a generally mild local inflammatory reaction. The antigen(s) present will be presented to your B and T cells, and those few recognising the antigen will be selected, they expand, mature in function, many will die, several will remain as memory cells.
2/10
Long-term vaccination effects.
It is strange to see the messages about not knowing the long-term effects of the COVID-19 vaccines. We do, and yes, of course, there are long-term consequences.
1/10
Immunologist MSc Utrecht, Faculty of Medicine🇳🇱, PhD Mill Hill London🇬🇧 and lab Cambridge🇬🇧, @iMMolecular, Prof @medicina_lisboa Faculty of Medicine🇵🇹https://marcveldhoen.substack.com/
GNU social JP is a social network, courtesy of GNU social JP管理人. It runs on GNU social, version 2.0.2-dev, available under the GNU Affero General Public License.
All GNU social JP content and data are available under the Creative Commons Attribution 3.0 license.