Waning of Maternal Antibodies Against Measles, Mumps, Rubella, and Varicella in Communities With Contrasting Vaccination Coverage
Does this paper provide support that vaccines undermine immune protection? No.
Waning of Maternal Antibodies Against Measles, Mumps, Rubella, and Varicella in Communities With Contrasting Vaccination Coverage
Does this paper provide support that vaccines undermine immune protection? No.
There are 3 considerations. Protection of infants wanes well before the first vaccination (14 months) leaving them more exposed than is ideal.
What about the lower level of antibodies? Do vaccines induce fewer antibodies compared to infection? There is no evidence for this.
6/9
Most likely, the exposure rate between non-vaccinated communities, with more children, less protection, and vaccinated communities with fewer children, more protection, is different.
7/9
For Measles (51.1% and 12.6% vax rate), and Rubella (65.6% and 17.2% vax rate), mums in the general population had lower levels of antibodies (4x and 55x), despite higher vax rate. As a result, babies get less antibodies and may be susceptible to infection sooner.
5/9
This may be the case because antibodies wean and immunity protects against transfer, infection and frequently less robust responses are required upon reinfection.
This is a cross-sectional serologic survey 7904 subjects (32.7% of invited), conducted in NL during 2006–2007.
3/9
The authors did not find differences in antibody levels and halflives in mums and babies between the general population and the religious population regarding Mumps antibodies (25.3 and 10.1% vax rate).
4/9
Childhood vaccinations have been in use for a long time, an example is the MMR vaccine against Measles, Mumps and Rubella. These vaccines are offered in early life. This may have consequences for the level of antibodies transferred during and after pregnancy.
2/9
GNU social JP is a social network, courtesy of GNU social JP管理人. It runs on GNU social, version 2.0.2-dev, available under the GNU Affero General Public License.
All GNU social JP content and data are available under the Creative Commons Attribution 3.0 license.