The NIH indirect cost cap thing will blow a hole the size of Texas in the budgets of research medical schools and life sciences departments across the country. Federal IDC rates are extremely high and it would be wrong to say there’s no room for debate about them. These cuts are gigantic, though. Capping IDCs at 15% is like a 45 percentage point cut.
https://grants.nih.gov/grants/guide/notice-files/NOT-OD-25-068.html