Federally funded research grants have all been put on hold. Grant reviews are not happening, grant-funded purchases of routine supplies are reportedly not happening, and all NIH grant-funded researchers are barred from publishing, traveling, or external meetings of any kind until further notice (https://www.nature.com/articles/d41586-025-00231-y). Unclear to me at this stage what else is NIH specific and what is more sweeping, but I think NSF has now followed suit.
It's typical for there to be a short (a day, a few days) pause on things like NIH spending while a new set of people is appointed, but the length and breadth of this freeze is radical. Much of this is percolating through unofficial channels too, so there's a lot of uncertainty as well. We don't know if grant-funded academic researchers will keep getting paid, for example.