As someone who regularly uses screen readers and works with blind colleagues who rely on screen readers to access the internet, please let me assure you that using #hashtags within the body of a post is not a problem.
You don’t need to move them to the end!
It is helpful to use #CamelCase to avoid gibberish for many word combos, but the extra # is so minimal as to disappear given how much else screen readers say & how fast they speak to experienced users.