I would like for everybody responsible* for the UI pattern of disruptive pop-ups interrupting every page or message transition, to be unable to focus on anything ever again.
That should get them out of the way of the rest of us.
I'm a little tired of websites interrupting with a blocking upsell advert while I'm trying to use the services I'm already paying for. Or that I'm trying to pay for, and am now having second thoughts about.
At this rate, I'm going to start specifically checking for this issue as part of the vendor-selection process.
*Please don't explain to me that the people implementing things don't always have a choice. I said "responsible" for a reason.