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During Roe v. Wade, McCorvey met her long-term partner Connie Gonzalez, and said she identified as a lesbian. However, later in her life, converted to Evangelical Protestantism and recanted and said she was no longer a lesbian. She still continued to live with Gonzalez.

Following her conversion in 1995, McCorvey became a vocal anti-abortion advocate. She quit her job at an abortion clinic and joined with an anti-abortion group, giving speeches in favour of making abortion illegal.