Some estimates suggest the Voyager crafts might survive (for some definition of "survive") all the way until Andromeda and Milky Way collide. That's around 4.5-5 billion years from now. For reference, our estimate is that life on earth is only about 4.5 billion years old.
The Voyagers could survive long enough for life itself to die out completely and see it re-evolve again.
The scale is boggling.