Erik Uden 🍑Day 015 of the Multiple Sclerosis Study
(Compound Day 12) Tuesday on 2024-09-17
Groningen, Netherlands (GMT+1)
- BP = blood pressure
- HR = heart rate
- SB = (study bound) meal controlled for the study
7:30 Wellbeing (Pre dose)
8:40 ECG (3x)
8:40 Vital signs (BP, HR)
8:55 Blood sampling
- PK: Sample 33
- Clinical chemistry (see SSL)
08:55 Transfer bloodtubes
9:10 Breakfast (Start)
9:40 Dose (RO7268489 or placebo)
9:40 Dose check
9:40 Water fast (Start)
11:40 Water fast (Stop)
11:40 Morning snack
13:10 Lunch
15:30 Afternoon snack
18:30 Dinner
19:00 Wellbeing
21:30 Evening snack
Muscle pain ended around 07:15
No more dizziness / disorientation ~10:00
08:55 (written afterwards)
Taking blood was a lot easier today, especially with their new butterfly needles that snap back when done. It feels a lot more painless, like ripping a bandaid off.
14:00 (written afterwards)
I had the first massage of my life. They offer one for our group here. Despite the lumbar puncture being long over, my back still tingled funny when I was massaged. I am not afraid of tomorrow's last lumbar puncture, rather I am anxious. Anxious of something happening the last time? Another roll of the dice, perhaps? Or anxious to go through the entire back pain, possibly headaches, whilst on withdrawal of an unknown compound. I will be so glad when this is over, though.
17:47
I'll write an update about what's going on later today! Weird things occurring...
18:01
Originally I wrote the following, I will write a better, more informed text about what occurred after it.
However, I decided against going into a psychiatry on my own free will, as it not only doesn't fit into my schedule, but I'll also not aid this potential fudging. Going to the psychiatry here (*next to being a ton of paperwork*) would also lead to them getting access to a lot of my medical documents, which Roche may go through to find whether there's some reason to dismiss me.
:blank:
:blank:
17:30 (written afterwards)
I was playing with my study- (and also room-) mates a version of rummy that I wasn't accustomed to, but learned during the study. The head physician came to the room and asked to speak me. I got up and walked to his room. He spoke to me in half-Dutch, half-English sentences, leaving lots of meaning up to interpretation. What I did understand as part of this conversation was the following:
“Hey Erik, I received an E-Mail / was in a meeting with the study's sponsor. They are concerned for your health and would want for you to go to a psychiatry. Now, from my perspective you are healthy and fine, which is what I told the sponsor. They will want to ask you for your consent to go to a psychiatry.”
What this meant wasn't explained further. Would I go to a psychiatry for one talk, would I have to stay there for another week? What am I consenting to?
He continued talking: “They want to see how you are, because no one in your group had strong symptoms like you. They want to see if you're okay mentally and would, through the psychiatry, request your medical history.”
I am not sure if this was the “consenting” he was referring to. Again, I am not only just recalling this information written 00:10 the next day, but the English was also hard to understand.
To be continued
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