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Day 013 of the Multiple Sclerosis Study
(Compound Day 10) Sunday on 2024-09-15
Groningen, Netherlands (GMT+1)

• BP = blood pressure
• HR = heart rate
• SB = (study bound) meal controlled for the study

07:30 Wellbeing (Pre dose)
08:40 ECG (3x)
08:40 Vital signs (BP, HR)
08:55 Blood sampling (PK: Sample 31)
08:55 Transfer bloodtubes
09:10 Breakfast (Start)
09:40 Dose (RO7268489 or placebo)
09:40 Dose check
09:40 Water fast (Start)
11:40 Water fast (Stop)
11:40 Morning snack
13:10 Lunch
15:30 Afternoon snack
18:30 Dinner
19:00 Wellbeing
21:30 Evening snack

Water intake: 3 (glasses, one tea, one compound)
Symptoms: none are severe :)

08:15 (written afterwards)
I woke up so late... Which is a good thing! I looked at the clock and thought “wow, it's 7:30, I'm basically sleeping in”, like, I REALLY thought getting up at 7:30 would be LATE, because here it is. I kept sleeping and was eventually woken up at ~08:15. What a great day today will be!

09:40 (written afterwards)
I am always astonished by the rigorous procedure that this compound should be handled with. They need to compare the data from my wristband (about my identity) with the text on the vial that holds the compound. The moment I'm in the room they have to hold the vial up and in their hands the entire time, because even if the assistant simply places the vial on the table, they'd have to do the entire comparison again. They also keep the vial afterwards.

13:05
Getting lunch soon! Excited for what this day may bring, I will go outside once more today.