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Day 012 of the Multiple Sclerosis Study
(Compound Day 9) Saturday on 2024-09-14
Groningen, Netherlands (GMT+1)

• BP = blood pressure
• HR = heart rate
• SB = (study bound) meal controlled for the study

07:30 Wellbeing Pre dose
08:30 Telemetry (Start subject lay down [192h])
08:40 Telemetry (Make ECG print [3x])
08:45 Telemetry (Stop subject lay down [192h])
08:45 Vital signs (BP, HR)
08:55 Blood sampling

• PK: Sample 30
• PL PD 2-AG: Sample 110
• SR PD 2-AG: Sample 315

08:55 Remove intravenous catheter
09:00 Transfer bloodtubes
09:00 Urine collection

• Stop container 6
• Stop collection

09:00 Transfer Urine containers
09:10 Breakfast (Start)
09:40 Dose (RO7268489 or placebo)
09:40 Dose check
09:40 Water fast (Start)
09:40 Telemetry

• Stop
• Disconnect + Archive

10:40 Intravenous catheter (Inspection)
11:40 Water fast (Stop)
11:40 Morning snack
13:10 Lunch
15:30 Afternoon snack
18:30 Dinner
19:00 Wellbeing
21:30 Evening snack

Water intake: 4 (glasses, one tea, one compound)

06:15
Y'all. I just woke up. I have NO negative side effects anymore (except for the mild ones)! I was able to sleep, my back doesn't hurt anymore, my arms are perfectly fine after the cannula was out. This is going to be a great day!

09:43
I can finally have a shower :]

18:22
This was a wonderful day! I walked outside, had fun with my peers, and recovered a lot by calling friends and doing what I like :blobcatmeltlove:

18:55
I was talking to a fellow German person sitting in front of me, then someone said "Here, we draw the Germany border” and gestured the imaginative border that would section us two off, on the table. He then continued “You guys are used to borders” and I can't stop laughing :spinnier_cat:

22:13
Many calls today, got lots of things done. Very good day!