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@aratinga

Unaligned:

hello; tgere
foo; bar
yesthatis;fine

Select the first column of every line, run a "normal mode" command on each line:

<C-v>G:norm dt;

Aligned, I would probably use visual block rather than visual line:

one;two
thr;fou
fiv;six

Enter visual block, motion to ;, move down 2 lines, delete selection

<C-v>t;2jx