My favorite remark regarding OS and chip agnosticism was "it's dark inside the box". GOOD, thoughtfully written code ought to result in similar environment for the user, across versions (hardware limitations respected) of software (NOT "APPS", software, anyone who calls *every* software "apps" needs to go to the same hell Jobs is in).
The resurgence of RISC (V) processors, is VERY interesting, but users may be wary, if only because habit and the bumps on the road of portability and chip manufacturing resources. Let's see where this goes.
I miss DEC Alpha, and PowerPCs... And BeOS. sigh.