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Food for thought:

LB.1 was third of two-weeks old New York/New Jersey estimate; roughly one-in-five in neighboring Mid-Atlantic and New England.

That said, LB.1 has two mutations in common with its fellow FLiRT variant, and second-guess vaccine target, KP.2, such that LB.1, like KP.3, is only two steps removed from KP.2.

However, in a scenario where, as an example, a non-KP SLip lineage picked up S:Q493E, joining KP.3 as another FLuQE, then JN.1, not KP.2, would be the closer vaccine target.