Should Biden drop out based on his debate performance? I don't know. Answering that sensibly requires two things that are not currently publicly known:
- The actual state of Biden's health, with an informed prognosis.
- If he's fit (see above, I don't know), the political landscape, based on highly granular polling data and informed analysis.
I'm neither an MD nor a political analyst, and I've neither examined Biden nor have access to the kinds of political data that campaigns use.