@adamconover
There is a biological process called the HPA axis, which controls the body's craving for and response to glucose. H for hypothalmus, P is pituitary, and A is adrenal.
Through **no fault** of their own, people afflicted with a malfunctioning HPA axis will stay obese. Weight is not a matter of will power - diet and exercise alone will not control the hormonal disregulation responsible.