It's been 6 hours since the "memory upload" data was transmitted to Voyager 1 from the NASA DSN site in Canberra.
During that time, the signal has traveled about a quarter of the way to Voyager 1, about the average distance to Pluto. The response will arrive at earth on Sunday around 1500 UTC (RTT = 45 hours).
Let's imagine a spacecraft sent to the nearest star Proxima Centauri, 4.2 light-years away. How would we diagnose problems and upload new software to it?