I'm pretty much Team Guix right now because they at least use a language that also gets used for other things.
(The one time I used Nix, it was to solve a specific work problem. It went okay because there were a couple of plain-English posts that addressed the extremely rare and uncommon task I was trying to accomplish (install a specific version of a tool) but had I not found them, it would have been faster to just build it by hand.)