The above is a good and safe default, so I repeat, don't do it! At least, unless you have a good reason and know what you're doing. I'm serious, and in most cases you really don't know what you're doing.
I'm currently rescuing an instance that is a mess, because I couldn't say no. And I'm sure there a many more instances like this out there. Instances that have grown too fast and are maintained by a single person. THIS could break the fediverse.