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<blockquote style="position: relative; padding-left: 55px;"><section><a href="https://mastodon.social/users/augieray/statuses/116703567048441736">Augie Ray (augieray@mastodon.social)'s status on Monday, 08-Jun-2026 01:19:58 JST</a><a href="https://mastodon.social/@augieray" title="augieray@mastodon.social"><img src="https://gnusocial.jp/avatar/83153-48-20251111171011.webp" width="48" height="48" alt="Augie Ray" style="position: absolute; left: 0; top: 0;">Augie Ray</a><div><a href="https://mastodon.social/@augieray/116703563246147910" rel="in-reply-to">in reply to</a></div></section><article><p>COVID may be running out of steam to evolve and overcome our defenses. There are still risks that could cause a major saltation and could cause more serious waves of infections, but this research seems to indicate Omicron is the natural destination for SARS-CoV-2, at least when it comes to the receptor<br>binding domain (RBD) on the Spike (S) of the virus. Might this be COVID's end-game? Time will tell, I guess. </p><p><a href="https://phys.org/news/2026-06-lab-evolution-recreates-covid-path.html" rel="nofollow">https://phys.org/news/2026-06-lab-evolution-recreates-covid-path.html</a> </p><p><a href="https://www.nature.com/articles/s41467-026-72312-z" rel="nofollow">https://www.nature.com/articles/s41467-026-72312-z</a></p></article><footer><a rel="bookmark" href="https://gnusocial.jp/conversation/6458782#notice-12714520">In conversation</a><time datetime="2026-06-08T01:19:58+09:00" title="Monday, 08-Jun-2026 01:19:58 JST">about 2 months ago</time> <span>from <span><a href="https://mastodon.social/@augieray/116703567048441736" rel="external" title="Sent from mastodon.social via ActivityPub">mastodon.social</a></span></span><a href="https://mastodon.social/@augieray/116703567048441736">permalink</a><h4>Attachments</h4><ol><li><article><header><div>Domain not in remote thumbnail source whitelist: scx2.b-cdn.net</div><h5><a href="https://phys.org/news/2026-06-lab-evolution-recreates-covid-path.html">Lab evolution recreates COVID's path to omicron in months, reveals key conditions</a></h5><div></div></header><div>A key step in the origin of many pandemics occurs when an animal-borne virus infects humans and then evolves to spread more efficiently from person to person. That is why scientists and physicians keep a close watch on viruses that could jump from animals to humans, such as emerging strains of avian flu and bat coronaviruses, as well as viruses that have already crossed into humans but, for now, spread poorly among people, such as hantavirus and Ebola.</div><footer></footer></article></li><li><article><header><div>No result found on File_thumbnail lookup.</div><h5><a href="https://www.nature.com/articles/s41467-026-72312-z?error=cookies_not_supported&amp;code=108dcc61-6715-44e1-b961-64152974cf90">Stringent selection drives convergence toward omicron-like SARS-CoV-2 receptor-binding motifs - Nature Communications</a></h5><div> from <span>Zahradník, Jiří</span></div></header><div>Authors explore the in vitro evolution of the binding elements on SARS-CoV-2. They find that stringent but not mild laboratory evolution led to rapid convergence toward Omicron lineage mutational patterns.</div><footer></footer></article></li></ol></footer></blockquote>

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Augie Ray (augieray@mastodon.social)'s status on Monday, 08-Jun-2026 01:19:58 JST Augie Ray
in reply to
COVID may be running out of steam to evolve and overcome our defenses. There are still risks that could cause a major saltation and could cause more serious waves of infections, but this research seems to indicate Omicron is the natural destination for SARS-CoV-2, at least when it comes to the receptor
binding domain (RBD) on the Spike (S) of the virus. Might this be COVID's end-game? Time will tell, I guess.
https://phys.org/news/2026-06-lab-evolution-recreates-covid-path.html
https://www.nature.com/articles/s41467-026-72312-z
In conversationabout 2 months ago from mastodon.socialpermalink
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1. Domain not in remote thumbnail source whitelist: scx2.b-cdn.net
  Lab evolution recreates COVID's path to omicron in months, reveals key conditions
  A key step in the origin of many pandemics occurs when an animal-borne virus infects humans and then evolves to spread more efficiently from person to person. That is why scientists and physicians keep a close watch on viruses that could jump from animals to humans, such as emerging strains of avian flu and bat coronaviruses, as well as viruses that have already crossed into humans but, for now, spread poorly among people, such as hantavirus and Ebola.
2. No result found on File_thumbnail lookup.
  Stringent selection drives convergence toward omicron-like SARS-CoV-2 receptor-binding motifs - Nature Communications
  from Zahradník, Jiří
  Authors explore the in vitro evolution of the binding elements on SARS-CoV-2. They find that stringent but not mild laboratory evolution led to rapid convergence toward Omicron lineage mutational patterns.

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