There are setups to run a hose and adapter from a large cylinder to a Sodastream or similar station, but I actually like the compact cylinders and not having to worry about hose leaks etc., just not the ridiculous loss-leader price tag or paying a company aligned with genocide.
Instead I got an adapter to refill the small cylinders from the large 5lb (10 or 20 works too) one, and it's very easy. Takes less than a minute if the recipient cylinder has been pre-cooled in freezer.