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@phnt@fluffytail.org Serious answer though, GNU Guix fixes both problems you mentioned actually.

On Guix you can have multiple versions of glibc installed if you need them. Because each version lives in its own storepath you can have each application link to the version of glibc that it wants, without static linking.

Guix also fixes the potential security issues with autotools you mentioned. In Guix all build commands are done in a completely offline and isolated environment, so any potential m4 based malware can't do any damage.