Reminder of the difference between mute and block:

Problem: Somebody is posting things you don't want to see.

Mute = Solves the problem.

Block = Solves the problem spitefully.

If the only thing you need is to filter your timeline, then Mute is the correct solution.

If your goal is to raise the overall level of hostility and resentment on the fedi, then block away.

I, for one, think there's already plenty of hostility and resentment to go around.